Effectiveness of Extrudate Dehulled Dark Barley (Giza 123 var)in Alleviating Metabolic Disorders Associated with diabetes in laboratory Rats

Tantwy, Heba Abd El Fattah; Galal, Wafaa Kamal; Hammoud, Gihan; Mirah, Wafaa Mohamed; Khorshid, Ahmed; Ahmed, Nivin Saad

doi:10.21608/enj.2025.373059.1104

Effectiveness of Extrudate Dehulled Dark Barley (Giza 123 var)in Alleviating Metabolic Disorders Associated with diabetes in laboratory Rats

Document Type : Original Article

Authors

¹ regional center for food and feed

² food tech.inst.,agric.res.-center,giza.crops technology

³ reviving ancient egyptian heritage and community development

⁴ founder of food technology research institute

10.21608/enj.2025.373059.1104

Abstract

ABSTRACT
This study aims to manufacture of healthy, high-quality puffed snacks from barley flour and rice powder (EBS) as well as to assess its impact in mitigation of metabolic disorders associated with diabetes. The perfect obtained extruded barley snacks (EBS) were 70:30% barely (dehulled Giza 123 Var): coarse rice grain. The results declared that EBS composed of lower moisture, protein and fiber and higher carbohydrates % than that of control Extruded corn snacks (ECS). EBS contains fewer calories than ECS, aligning with its reduced fat content. Moreover EBS had higher antioxidant activity than ECS and showed fair overall acceptability among panelist. Herein, the biological experiment on male adult rats revealed that replacing of 25% of their basal diet by EBS and ECS had no negative effect on any of tested parameters except for body weight and body weight gain which significantly increased in rats feed on ECS comparing to control. In contrary, injection of rats with single dose of streptozotocin (STZ, diabetic-induce agent, 65mg/kg bw) caused enhancing of lipid peroxidation and depletion of glutathione and catalase, and resulted in dramatic lowering of both body weight and weight gain, elevation of all tested biochemical parameters along with marked distortion of pancreas, liver, kidney and testis histology after five weeks. Feeding of diabetic rats on EBS and ECS successfully alleviated that deleterious effect of STZ. The EBS shows more reliable improvement than ECS. Our results augment the hypothesis of EBS could be beneficial and healthier choice for people with diabetes type2.

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